World Library  
Flag as Inappropriate
Email this Article

Samuel Karlin

Article Id: WHEBN0015880746
Reproduction Date:

Title: Samuel Karlin  
Author: World Heritage Encyclopedia
Language: English
Subject: Marcus Feldman, John W. Pratt, Thomas M. Liggett, Elisha Netanyahu, John von Neumann Theory Prize
Collection: 1924 Births, 2007 Deaths, 20Th-Century Mathematicians, American Atheists, American Geneticists, American Operations Researchers, American People of Polish-Jewish Descent, Deaths from Myocardial Infarction, Fellows of the American Academy of Arts and Sciences, Functional Analysts, Game Theorists, Illinois Institute of Technology Alumni, Jewish Atheists, Mathematical Economists, Members of the United States National Academy of Sciences, National Medal of Science Laureates, Polish Emigrants to the United States, Princeton University Alumni, Probability Theorists, Stanford University Department of Mathematics Faculty, Stanford University Department of Statistics Faculty
Publisher: World Heritage Encyclopedia

Samuel Karlin

Samuel Karlin
Born (1924-06-08)June 8, 1924
Janów, Lublin Province, Second Polish Republic
Died December 18, 2007(2007-12-18) (aged 83)
Palo Alto, California, USA
Citizenship American
Nationality Poland
Fields mathematical sciences
population genetics
Institutions Stanford University
Alma mater Illinois Institute of Technology Princeton University
Doctoral students Christopher Burge[1]
Thomas LIggett
John W. Pratt
Known for BLAST
Karlin-Rubin theorem (UMP tests of monotone likelihoods)
geometry of moments[2]
Total positivity
Tchebycheff systems
Optimal experiments
Notable awards National Medal of Science (1989)
John von Neumann Theory Prize (1987)

Samuel Karlin (June 8, 1924 – December 18, 2007) was an American mathematician at Stanford University in the late 20th century.


  • Biography 1
  • Selected publications 2
  • See also 3
  • References 4
  • External links 5


Karlin was born in Janów, Poland and immigrated to Chicago as a child. Raised in an Orthodox Jewish household, Karlin became an atheist in his teenage years and remained an atheist for the rest of his life.[3]

Karlin earned his undergraduate degree from Illinois Institute of Technology; and then his doctorate in mathematics from Princeton University in 1947 (at the age of 22) under the supervision of Salomon Bochner. He was on the faculty of Caltech from 1948 to 1956, before becoming a professor of mathematics and statistics at Stanford.[3][4]

Throughout his career, Karlin made fundamental contributions to the fields of mathematical economics, bioinformatics, game theory, evolutionary theory, biomolecular sequence analysis, and total positivity.[4] He did extensive work in mathematical population genetics. In the early 1990s, Karlin and Stephen Altschul developed the Karlin-Altschul statistics, a basis for the highly used sequence similarity software program BLAST.[3]

Karlin authored ten books and more than 450 articles.[4] Karlin was a member of both the National Medal of Science "for his broad and remarkable research in mathematical analysis, probability theory and mathematical statistics, and in the application of these ideas to mathematical economics, mechanics, and population genetics."[6]

Karlin's three children all became scientists.[7] One of his sons, Kenneth D. Karlin, is a professor of chemistry at Johns Hopkins University and the 2009 winner of the American Chemical Society's F. Albert Cotton Award for Synthetic Chemistry.[8] His other son, Manuel, is a physician in Portland, Oregon. His daughter, Anna R. Karlin, is a theoretical computer scientist, the Microsoft Professor of Computer Science & Engineering at the University of Washington.[9]

Selected publications

  • S. Karlin and H. M. Taylor. "A First Course in Stochastic Processes." Academic Press, 1975 (second edition).
  • S. Karlin and H. M. Taylor. "A Second Course in Stochastic Processes." Academic Press, 1981.
  • S. Karlin and H. M. Taylor. "An Introduction to Stochastic Modeling, Third Edition." Academic Press, 1998. ISBN 0-12-684887-4
  • S. Karlin, D. Eisenberg, and R. Altman. "Bioinformatics: Unsolved Problems and Challenges." National Academic Press Inc., 2005. ISBN 978-0-309-10029-8.
  • S. Karlin (Ed.). "Econometrics, Time Series, and Multivariate Statistics." Academic Press, 1983. ISBN 978-0-12-398750-1.
  • S. Karlin (Author) and E. Nevo (Editor). "Evolutionary Processes and Theory." Academic Press, 1986. ISBN 978-0-12-398760-0.
  • S. Karlin. "Mathematical Methods and Theory in Games, Programming, and Economics." Dover Publications, 1992. ISBN 978-0-486-67020-1.
  • S. Karlin and E. Nevo (Eds.). "Population Genetics and Ecology." Academic Press, 1976. ISBN 978-0-12-398560-6.
  • S. Karlin and W. J. Studden. "Tchebycheff systems: With applications in analysis and statistics (pure and applied mathematics)." Interscience Publishers, 1966 (1st edition). ASIN B0006BNV2C.
  • S Karlin and S. Lessard. "Theoretical Studies on Sex Ratio Evolution." Princeton University Press, 1986. ISBN 978-0-691-08412-1
  • S. Karlin. "Theory of Infinite Games." Addison Wesley Longman Ltd. Inc., 1959. ASIN B000SNID12.
  • S. Karlin. "Total Positivity, Vol. 1." Stanford, 1968. ASIN B000LZG0Xu.

See also


  1. ^
  2. ^
  3. ^ a b c Sam Karlin, mathematician who improved DNA analysis, dies
  4. ^ a b c Sam Karlin, influential math professor, dead at 83
  5. ^
  6. ^ US NSF - The President's National Medal of Science: Recipient Details
  7. ^ Sam Karlin, mathematician who improved DNA analysis, dead at 83, Stanford University, retrieved 2011-01-16.
  8. ^ Kenneth Karlin's web site at JHU, retrieved 2011-01-16.
  9. ^ Anna Karlin's faculty web page at U. Washington, retrieved 2011-01-16.

External links

  • "Math in the News: Mathematician Sam Karlin, Known for Contributions in Computational Biology, has Died." Math Gateway of the Mathematical Association of America, February 5, 2008.
  • .
  • Samuel Karlin at the Mathematics Genealogy Project
  • Obituary, I.M.S. Bulletin, May 2008

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from World Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.