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Plos One : Α-lipoic Acid Reduces Infarct Size and Preserves Cardiac Function in Rat Myocardial Ischemia, Volume 8

By Katare, Rajesh Gopalrao

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Book Id: WPLBN0003969671
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : Α-lipoic Acid Reduces Infarct Size and Preserves Cardiac Function in Rat Myocardial Ischemia, Volume 8  
Author: Katare, Rajesh Gopalrao
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

Description
Description : This study indicates that LA attenuates cardiac dysfunction by reducing cardiomyoctyes necrosis, apoptosis and inflammation after MI/R. LA exerts its action by activating the PI3K/Akt pathway as well as subsequent Nrf2 nuclear translocation and induction of cytoprotective genes such as HO-1.

 

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